- Review Article
- Genetics and Metabolism
- Understanding the genetics of systemic lupus erythematosus using Bayesian statistics and gene network analysis
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Seoung Wan Nam, Kwang Seob Lee, Jae Won Yang, Younhee Ko, Michael Eisenhut, Keum Hwa Lee, Jae Il Shin, Andreas Kronbichler
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Clin Exp Pediatr. 2021;64(5):208-222. Published online July 15, 2020
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Bayesian false-discovery probability and false-positive report probability are the 2 major Bayesian methods used to evaluate noteworthiness of a genetic variant.
Application of stricter P value is needed to confirm statistical significance in meta-analyses.
Gene network analysis of noteworthy genetic variants shows a blueprint of the genetic background in complex diseases. |
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